ER? expression seems important in preinvasive cancers
نویسندگان
چکیده
منابع مشابه
Geographic distribution of important cancers in Iran
Introduction: Each year, 10 million people are faced with cancer and about 6 million of them die throughout the world. This study aimed at investigating the geographical distribution of cancer and its environmental risk factors in Iran. Methods: The present study was mapping the available data collected from the reports of Iranian Center for Disease Control (Cancer Bureau) regarding the frequen...
متن کاملDifferentiated expression of estrogen receptors (ER) and progesterone receptors (PgR) in ductal breast cancers.
Contents of estrogen receptors (ER) and progesterone receptors (PgR) in cells of breast cancers represent strong predictive factors. The higher is the contents of ER and PgR in breast cancer, the higher is a probability of obtaining a response to hormonal therapy and prognosis for the patient is better. In a routine manner, all tumours of mammary gland are subjected to evaluation of ER and PgR ...
متن کاملStromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers.
The stromal compartment is increasingly recognized to play a role in cancer. However, its role in the transition from preinvasive to invasive disease is unknown. Most gastrointestinal tumors have clearly defined premalignant stages, and Barrett's esophagus (BE) is an ideal research model. Supervised clustering of gene expression profiles from microdissected stroma identified a gene signature th...
متن کاملPrognostic Impact of HOTAIR Expression is Restricted to ER-Negative Breast Cancers
Expression of HOX transcript antisense intergenic RNA (HOTAIR), a large intergenic noncoding RNA (lincRNA), has been described as a metastases-associated lincRNA in various cancers including breast, liver and colon cancer cancers. We sought to determine if expression of HOTAIR could be used as a surrogate for assessing nodal metastases and evaluated RNA in situ hybridization (RNA-ISH) assay in ...
متن کاملAllred scoring for ER reporting and it's impact in clearly distinguishing ER negative from ER positive breast cancers.
OBJECTIVE To determine the scoring of Estrogen Receptor (ER) status in carcinoma breast by Allred method that is essentially bimodal and to compare the results with a conventional scoring system. MATERIALS AND METHODS A retrospective, comparative study carried out at Aga Khan University Hospital Section of Histopathology over a period of 18 months, i.e., Jan 2005 to June 2006. Anti ER antibod...
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ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2001
ISSN: 1465-542X
DOI: 10.1186/bcr-2001-68460